Molly Vickers
I figured that answering this question would be simple and straight-forward after a little bit of research on the topic. However, I was surprised at what I found. There was not one article or study I found that running is all-around a better cardio workout than using an elliptical. According to Edward R. Laskowski, M.D., the elliptical has many advantages. It is less stressful on knees and joints, and you can pedal in reverse which works on calf and hamstring muscles. Treadmill versus elliptical benefits also depends on a person's fitness goals. An elliptical is a good alternative to jogging because both are considered "low impact," but a treadmill is a better tool to prepare for high impact training such as a distance road race.
A study conducted at the University of Nebraska concludes that oxygen consumption and energy expenditure do not differ whether using a treadmill or an elliptical in spite of a higher heart rate on the elliptical. This information implies that an elliptical is an acceptable alternate to running on a treadmill, which surprised me because running is always much more of a challenge to me than using an elliptical when I work out.
Sources:
http://www.ncbi.nlm.nih.gov/pubmed/20453685
http://www.mayoclinic.com/health/elliptical-machines/AN01620
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